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Product Description
A potent and selective pan-TRK inhibitor, suppressing the activity of TrkA and TrkB with IC50 of 8 and 12 nM, respectively
A potent and selective pan-TRK inhibitor, suppressing the activity of TrkA and TrkB with IC50 of 8 and 12 nM, respectively
Biovision | B1339 | GNF-5837 DataSheet
Alternate Name/Synonyms: (Z)-1-(3-((3-((1H-pyrrol-2-yl)methylene)-2-oxoindolin-6-yl)amino)-4-methylphenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea
Appearance: Solid
Formulation: N/A
CAS Number: 1033769-28-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C28H21F4N5O2
Molecular Weight: 535.49
Cell-Permeable?: Yes
Purity: >98% by HPLC
Solubilities: DMSO > 10 mM
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent and selective pan-TRK inhibitor
MDL Number: MFCD24386809
PubChem CID: 59397065
SMILES: CC1=C(C=C(C=C1)NC(=O)NC2=C(C=CC(=C2)C(F)(F)F)F)NC3=CC4=C(C=C3)C(=CC5=CC=CN5)C(=O)N4
InChi: 1S/C28H21F4N5O2/c1-15-4-6-19(35-27(39)37-25-11-16(28(30,31)32)5-9-22(25)29)13-23(15)34-18-7-8-20-21(12-17-3-2-10-33-17)26(38)36-24(20)14-18/h2-14,33-34H,1H3,(H,36,38)(H2,35,37,39)/b21-12-
InChi Key: YYDUWLSETXNJJT-MTJSOVHGSA-N
