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Product Description
GSK-3787 is a selective and irreversible antagonist of the peroxisome proliferator-activated receptor delta (PPARδ) (plC₅₀ = 6.6). It covalently binds to Cys 249 in the PPARδ binding site.
GSK-3787 is a selective and irreversible antagonist of the peroxisome proliferator-activated receptor delta (PPARδ) (plC₅₀ = 6.6).
Biovision | 2400 | GSK-3787 DataSheet
Alternate Name/Synonyms: 4-Chloro-N-(2-{[5-(trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide
Appearance: White solid
Formulation: N/A
CAS Number: 188591-46-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₅H₁₂ClF₃N₂O₃S
Molecular Weight: 392.78
Cell-Permeable?: Yes
Purity: ≥98% by TLC
Solubilities: DMSO (~30 mg/ml)
Handling: Protect from light and air
Country of Origin: USA
Tag Line: A potent PPARδ antagonist
MDL Number: MFCD00099612
PubChem CID: 2800647
SMILES: C1=CC(=CC=C1C(=O)NCCS(=O)(=O)C2=NC=C(C=C2)C(F)(F)F)Cl
InChi: InChI=1S/C15H12ClF3N2O3S/c16-12-4-1-10(2-5-12)14(22)20-7-8-25(23,24)13-6-3-11(9-21-13)15(17,18)19/h1-6,9H,7-8H2,(H,20,22)
InChi Key: JFUIMTGOQCQTPF-UHFFFAOYSA-N
