Product Description
JNJ-26481585 is a second-generation pyrimidyl-hydroxamic acid histone deacetylase (HDAC) inhibitor with high cellular potency towards Class I and II HDACs. It displays potent antineoplastic activities.
JNJ-26481585 is a second-generation pyrimidyl-hydroxamic acid histone deacetylase (HDAC) inhibitor with high cellular potency towards Class I and II HDACs. It displays potent antineoplastic activities.
Biovision | 9612 | JNJ-26481585 DataSheet
Alternate Name/Synonyms: N-hydroxy-2-(4-((((1-methyl-1H-indol-3-yl)methyl)amino)methyl)piperidin-1-yl)pyrimidine-5-carboxamide; Quisinostat
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 875320-29-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₁H₂₆N₆O₂
Molecular Weight: 394.21
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>50 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent, second-generation HDAC inhibitor
MDL Number: N/A
PubChem CID: 11538455
SMILES: CN1C=C(C2=CC=CC=C21)CNCC3CCN(CC3)C4=NC=C(C=N4)C(=O)NO
InChi: InChI=1S/C21H26N6O2/c1-26-14-17(18-4-2-3-5-19(18)26)11-22-10-15-6-8-27(9-7-15)21-23-12-16(13-24-21)20(28)25-29/h2-5,12-15,22,29H,6-11H2,1H3,(H,25,28)
InChi Key: PAWIYAYFNXQGAP-UHFFFAOYSA-N