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Product Description
MK-4101 is a potent and selective inhibitor of the Hedgehog (Hh) signaling pathway. It displays potent activity against medulloblastoma and Basal Cell Carcinoma (BCC). MK-4101 shows anti-tumor activity through the inhibition of proliferation and induction of extensive apoptosis in tumor cells.
MK-4101 is a potent and selective inhibitor of the Hedgehog (Hh) signaling pathway. It displays potent activity against medulloblastoma and Basal Cell Carcinoma (BCC). MK-4101 shows anti-tumor activity through the inhibition of proliferation and induction of extensive apoptosis in tumor cells.
Biovision | B1255 | MK-4101 DataSheet
Alternate Name/Synonyms: 5-(3,3-Difluorocyclobutyl)-3-[4-[4-methyl-5-[2-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl]bicyclo[2.2.2]oct-1-yl]-1,2,4-oxadiazole
Appearance: Crystaline solid
Formulation: N/A
CAS Number: 935273-79-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₂₄H₂₄F₅N₅O
Molecular Weight: 493.48
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: Aselective Hedgehog (Hh) signaling pathway inhibitor.
MDL Number: N/A
PubChem CID: 16222379
SMILES: CN1C(=NN=C1C23CCC(CC2)(CC3)C4=NOC(=N4)C5CC(C5)(F)F)C6=CC=CC=C6C(F)(F)F
InChi: InChI=1S/C24H24F5N5O/c1-34-17(15-4-2-3-5-16(15)24(27,28)29)31-32-20(34)22-9-6-21(7-10-22,8-11-22)19-30-18(35-33-19)14-12-23(25,26)13-14/h2-5,14H,6-13H2,1H3
InChi Key: HKJOIWLYDJCTQR-UHFFFAOYSA-N
