Product Description
ML-365 is a potent and selective TASK-1 (K2P3.1/KCNK3) channel blocker (IC₅₀ values are 4 and 390 nM at TASK-1 and TASK-3, respectively). Displays little or no inhibition at Kir2.1, voltage-gated potassium channels, KCNQ2 and KV11.1 (hERG).
ML-365 is a potent and selective TASK-1 (K2P3.1/KCNK3) channel blocker (IC₅₀ values are 4 and 390 nM at TASK-1 and TASK-3, respectively). Displays little or no inhibition at Kir2.1, voltage-gated potassium channels, KCNQ2 and KV11.1 (hERG).
Biovision | B2076 | ML-365 DataSheet
Alternate Name/Synonyms: 2-Methoxy-N-[3-[(3-methylbenzoyl)amino]phenyl]benzamide
Appearance: Off-white solid
Formulation: N/A
CAS Number: 947914-18-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₂H₂₀N₂O₃
Molecular Weight: 360.41
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>30 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent and selective TASK-1 (K2P3.1/KCNK3) channel blocker
MDL Number: N/A
PubChem CID: 46785920
SMILES: CC1=CC=CC(=C1)C(=O)NC2=CC(=CC=C2)NC(=O)C3=CC=CC=C3OC
InChi: InChI=1S/C22H20N2O3/c1-15-7-5-8-16(13-15)21(25)23-17-9-6-10-18(14-17)24-22(26)19-11-3-4-12-20(19)27-2/h3-14H,1-2H3,(H,23,25)(H,24,26)
InChi Key: UTAJHKSGYJSZBR-UHFFFAOYSA-N