Product Description
Motolimod (VTX-2337) is a potent and selective, small molecule Toll-like receptor (TLR) 8 agonist (EC₅₀ = 100 nM) that stimulates natural killer (NK) cells, dendritic cells, and monocytes. Useful in immunotherapy for multiple oncology indications, including squamous cell carcinoma of the head and neck (SCCHN).
Motolimod (VTX-2337) is a potent and selective, small molecule Toll-like receptor (TLR) 8 agonist (EC₅₀ = 100 nM) that stimulates natural killer (NK) cells, dendritic cells, and monocytes. Useful in immunotherapy for multiple oncology indications, including squamous cell carcinoma of the head and neck (SCCHN).
Biovision | B1594 | Motolimod DataSheet
Alternate Name/Synonyms: 3H-1-Benzazepine-4-carboxamide, 2-amino-N,N-dipropyl-8-[4-(1-pyrrolidinylcarbonyl)phenyl; VTX-2337
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 926927-61-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₂₈H₃₄N₄O₂
Molecular Weight: 458.6
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>10 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent and selective, small molecule Toll-like receptor (TLR) 8 agonist
MDL Number: N/A
PubChem CID: 16049404
SMILES: CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C3=CC=C(C=C3)C(=O)N4CCCC4)N=C(C1)N
InChi: InChI=1S/C28H34N4O2/c1-3-13-31(14-4-2)28(34)24-17-23-12-11-22(18-25(23)30-26(29)19-24)20-7-9-21(10-8-20)27(33)32-15-5-6-16-32/h7-12,17-18H,3-6,13-16,19H2,1-2H3,(H2,29,30)
InChi Key: QSPOQCXMGPDIHI-UHFFFAOYSA-N