Product Description
MS436 is a potent and selective BRD4 bromodomain inhibitor (Ki = 30-50 nM for BrD1). It displays 10-fold selectivity for BrD1 of BRD4 over BrD2 of BRD4.
MS436 is a potent and selective BRD4 bromodomain inhibitor (Ki = 30-50 nM for BrD1). It displays 10-fold selectivity for BrD1 of BRD4 over BrD2 of BRD4.
Biovision | 2680 | MS436 DataSheet
Alternate Name/Synonyms: (E)-4-[2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide
Appearance: Red solid
Formulation: N/A
CAS Number: 1395084-25-9
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₈H₁₇N₅O₃S
Molecular Weight: 383.42
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>30 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent BRD4 bromodomain inhibitor
MDL Number: N/A
PubChem CID: 60171585
SMILES: CC1=CC(=NNC2=CC=C(C=C2)S(=O)(=O)NC3=CC=CC=N3)C(=CC1=O)N
InChi: nChI=1S/C18H17N5O3S/c1-12-10-16(15(19)11-17(12)24)22-21-13-5-7-14(8-6-13)27(25,26)23-18-4-2-3-9-20-18/h2-11,21H,19H2,1H3,(H,20,23)/b22-16-
InChi Key: BBJDRANVVNBXAR-JWGURIENSA-N