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Product Description
Potent and selective inhibitor of CYP19 (aromatase), CYP1A1, CYP1A2, and CYP1B1 (IC50 = 500, 60, 6, and 5 nM respectively). Can activate CYP3A4 (Kd = 7.4 µM).
Potent and selective inhibitor of CYP19 (aromatase), CYP1A1, CYP1A2, and CYP1B1 (IC50 = 500, 60, 6, and 5 nM respectively). Can activate CYP3A4 (Kd = 7.4 µM).
Biovision | 2918 | α-naphthoflavone DataSheet
Alternate Name/Synonyms: 2-phenyl-4H-naphtho[1,2-b]pyran-4-one, NSC 407011, 7,8-Benzoflavone
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 604-59-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₉H₁₂O₂
Molecular Weight: 272.3
Cell-Permeable?: N/A
Purity: ≥98%
Solubilities: DMSO (~10 mg/ml) or DMF (~20 mg/ml), Ethanol (~1 mg/ml)
Handling: Protect from air, light and moisture
Country of Origin: USA
Tag Line: A potent inhibitor of Cytochrome P450 enzymes (Aromatase, 1A2, 1A1, 1B1)
MDL Number: MFCD00004985
PubChem CID: 11790
SMILES: O=C1C2=C(C(C=CC=C3)=C3C=C2)OC(C4=CC=CC=C4)=C1
InChi: InChI=1S/C19H12O2/c20-17-12-18(14-7-2-1-3-8-14)21-19-15-9-5-4-6-13(15)10-11-16(17)19/h1-12H
InChi Key: VFMMPHCGEFXGIP-UHFFFAOYSA-N
