Product Description
Oridonin, a diterpenoid isolated from Rabdosia rubescens displays anti-inflammatory, anti-bacterial, anti-tumor effects and has been used for the treatment of human cancers, especially esophageal carcinoma. Exposure to oridonin induces apoptosis in AE (AML1-ETO)-bearing leukemic cells through the activation of intrinsic apoptotic pathway and triggering a caspase-3-mediated degradation of AE at D188
Oridonin, a diterpenoid isolated from Rabdosia rubescens displays anti-inflammatory, anti-bacterial, anti-tumor effects and has been used for the treatment of human cancers, especially esophageal carcinoma. Exposure to oridonin induces apoptosis in AE (AML1-ETO)-bearing leukemic cells through the activation of intrinsic apoptotic pathway and triggering a caspase-3-mediated degradation of AE at D188.
Biovision | 1730 | Oridonin DataSheet
Alternate Name/Synonyms: NSC-250682
Appearance: Off-white solid
Formulation: N/A
CAS Number: 28957-04-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₀H₂₈N₅O₆
Molecular Weight: 364.43
Cell-Permeable?: Yes
Purity: ≥97% by HPLC
Solubilities: DMSO
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A diterpenoid
MDL Number: MFCD00221762
PubChem CID: 457846
SMILES: CC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5=O)(OC3)O)O)O)C
InChi: InChI=1S/C20H28O6/c1-9-10-4-5-11-18-8-26-20(25,19(11, 14(9)22)15(10)23)16(24)13(18)17(2,3)7-6-12(18)21/h10-13,15-16,21,23-25H,1,4-8H2,2-3H3/t10?,11?,12-,13+,15-,16-,18?,19?,20+/m0/s1
InChi Key: SDHTXBWLVGWJFT-ATGZISJRSA-N