Product Description
Cell-permeable. A Selective inhibitor of the ubiquitin-specific protease USP7 (IC₅₀ = 4.2 µM). Induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance. Displays antiangiogenic activity in vivo.
P5091 is a selective inhibitor of the ubiquitin-specific protease USP7 (IC₅₀ = 4.2 µM).
Biovision | 2277 | P5091 DataSheet
Alternate Name/Synonyms: 1-[5-[(2,3-Dichlorophenyl)thio]-4-nitro-2-thienyl]ethanone
Appearance: White solid
Formulation: N/A
CAS Number: 882257-11-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₂H₇Cl₂NO₃S₂
Molecular Weight: 348.22
Cell-Permeable?: Yes
Purity: ≥98% by TLC
Solubilities: DMSO (~20 mg/ml, warm) or EtOH (~40 mg/ml, warm)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A selective USP7 inhibitor
MDL Number: N/A
PubChem CID: 2819993
SMILES: CC(=O)C1=CC(=C(S1)SC2=C(C(=CC=C2)Cl)Cl)[N+](=O)[O-]
InChi: InChI=1S/C12H7Cl2NO3S2/c1-6(16)10-5-8(15(17)18)12(20-10)19-9-4-2-3-7(13)11(9)14/h2-5H,1H3
InChi Key: LKZLGMAAKNEGCH-UHFFFAOYSA-N