Product Description
Belongs to an alkylphospholipid class of antineoplastic compounds that display potent antiproliferative activity in several in vitro and in vivo human tumor models. Perifosine induces apoptotic cell death in a variety of tumor cell lines. Apoptosis is induced in a time- and dose-dependent manner in U937 and Jurkat T human leukemia cell lines but not in normal vascular endothelial cells.
Perifosine (KRX-0401) belongs to an alkylphospholipid class of antineoplastic compounds that display potent antiproliferative activity in several in vitro and in vivo human tumor models.
Biovision | 1592 | Perifosine (KRX-0401) DataSheet
Alternate Name/Synonyms: KRX-0401
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 157716-52-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₅H₅₃NO₄P
Molecular Weight: 462.66
Cell-Permeable?: Yes
Purity: ≥99%
Solubilities: H₂O (10 mg/ml)
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: An antineoplastic agent
MDL Number: MFCD00927554
PubChem CID: 148178
SMILES: CCCCCCCCCCCCCCCCCCOP(=O)(O)OC1CC[N+](CC1)(C)C
InChi: InChI=1S/C25H52NO4P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-29- 31(27,28)30-25-20-22-26(2,3)23-21-25/h25H,4-24H2,1-3H3/p+1
InChi Key: SZFPYBIJACMNJV-UHFFFAOYSA-O