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Product Description
A cyclic analog of the p53 inhibitor Pifithrin-α (Cat.No.1554-10). Sensitizes wild type p53 tumor cells to antimicrotubule agent-induced apoptosis.
Cyclic Pifithrin-α is a cyclic analog of the p53 inhibitor Pifithrin-α (Cat.No.1554-10). Sensitizes wild type p53 tumor cells to antimicrotubule agent-induced apoptosis.
Biovision | 2270 | Pifithrin-α, Cyclic, hydrobromide DataSheet
Alternate Name/Synonyms: 5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazole hydrobromide; QB102
Appearance: White solid
Formulation: N/A
CAS Number: 511296-88-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₁₆N₂S ∙ HBr
Molecular Weight: 349.29
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (100 mM) or EtOH (10 mM)
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A p53 inhibitor
MDL Number: MFCD02683960
PubChem CID: 11515812
SMILES: CC1=CC=C(C=C1)C2=CN3C4=C(CCCC4)SC3=N2.Br
InChi: InChI=1S/C16H16N2S.BrH/c1-11-6-8-12(9-7-11)13-10-18-14-4-2-3-5-15(14)19-16(18)17-13;/h6-10H,2-5H2,1H3;1H
InChi Key: SGNCOAOESGSEOP-UHFFFAOYSA-N
