Product Description
Pirarubicin is an analog of doxorubicin, that acts as an antineoplastic drug. Pirarubicin is transported into cells via a sodium-dependent nucleoside transporter. It is used to intercalate DNA and inhibit the activity of topoisomerase II and induce DNA crosslinking.
Pirarubicin is an analog of doxorubicin, that acts as an antineoplastic drug. Pirarubicin is transported into cells via a sodium-dependent nucleoside transporter. It is used to intercalate DNA and inhibit the activity of topoisomerase II and induce DNA crosslinking.
Biovision | B2216 | Pirarubicin DataSheet
Alternate Name/Synonyms: (8S,10S)-10-(((2R,4S,5S,6S)-4-amino-6-methyl-5-(((S)-tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
Appearance: Red solid
Formulation: N/A
CAS Number: 72496-41-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₃H₃₇NO₁₂
Molecular Weight: 627.64
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: EtOH (~25 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An anticancer drug
MDL Number: MFCD00869742
PubChem CID: 636397
SMILES: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)OC6CCCCO6
InChi: InChI=1S/C32H37NO12/c1-14-31(45-21-8-3-4-9-42-21)17(33)10-22(43-14)44-19-12-32(40,20(35)13-34)11-16-24(19)30(39)26-25(28(16)37)27(36)15-6-5-7-18(41-2)23(15)29(26)38/h5-7,14,17,19,21-22,31,34,37,39-40H,3-4,8-13,33H2,1-2H3/t14-,17-,19-,21-,22-,31+,32-/m0/s1
InChi Key: KMSKQZKKOZQFFG-HSUXVGOQSA-N