Product Description
An irreversible inhibitor of serine proteases (such as thrombin, trypsin and chymotrypsin) and mammalian acetylcholinesterase. It causes sulfonylation of the active-site serine residues. Inhibits cysteine proteases like papain (reversible by DTT treatment). Also inhibits internucleosomal DNA fragmentation in immature thymocytes.
PMSF is a an irreversible inhibitor of serine proteases (such as thrombin, trypsin and chymotrypsin) and mammalian acetylcholinesterase. It causes sulfonylation of the active-site serine residues. Inhibits cysteine proteases like papain (reversible by DTT treatment). Also inhibits internucleosomal DNA fragmentation in immature thymocytes.
Biovision | 1548 | PMSF DataSheet
Alternate Name/Synonyms: α-Toluenesulfonyl fluoride, Benzylsulfonyl fluoride, Phenylmethylsulfonyl fluoride
Appearance: White solid
Formulation: N/A
CAS Number: 329-98-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₇H₇FO₂S
Molecular Weight: 174.2
Cell-Permeable?: No
Purity: ≥99%
Solubilities: EtOH (10%)
Handling: Protect from moisture
Country of Origin: USA
Tag Line: A serine protease inhibitor
MDL Number: MFCD00007424
PubChem CID: 4784
SMILES: C1=CC=C(C=C1)CS(=O)(=O)F
InChi: InChI=1S/C7H7FO2S/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2
InChi Key: YBYRMVIVWMBXKQ-UHFFFAOYSA-N