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Product Description
Pyripyropropene A is isolated from Aspergillus fumigatus FO-1289. Acts as a highly specific inhibitor of acyl-coenzyme A: cholesterol acetyltransferase 2 (ACAT2). Antiatherogenic and antiatherosclerotic agent. Shows cholesterol-lowering and atheroprotective activities.
Pyripyropropene A is isolated from Aspergillus fumigatus FO-1289. Acts as a highly specific inhibitor of acyl-coenzyme A: cholesterol acetyltransferase 2 (ACAT2). Antiatherogenic and antiatherosclerotic agent. Shows cholesterol-lowering and atheroprotective activities.
Biovision | B1910 | Pyripyropene A DataSheet
Alternate Name/Synonyms: 3S,4R,4aR,6S,6aS,12R,12aS,12bS)-4-(acetoxymethyl)-12-hydroxy-4,6a,12b-trimethyl-11-oxo-9-(pyridin-3-yl)-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-2H,11H-benzo[f]pyrano[4,3-b]chromene-3,6-diyl diacetate
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 147444-03-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₃₁H₃₇NO₁₀
Molecular Weight: 583.62
Cell-Permeable?: Yes
Purity: ≥95%
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A highly specific acyl-coenzyme A: cholesterol acetyltransferase 2 (ACAT2) inhibitor
MDL Number: MFCD00929109
PubChem CID: 11828024
SMILES: CC(=O)OCC1(C(CCC2(C1CC(C3(C2C(C4=C(O3)C=C(OC4=O)C5=CN=CC=C5)O)C)OC(=O)C)C)OC(=O)C)C
InChi: InChI=1S/C31H37NO10/c1-16(33)38-15-30(5)22-13-24(40-18(3)35)31(6)27(29(22,4)10-9-23(30)39-17(2)34)26(36)25-21(42-31)12-20(41-28(25)37)19-8-7-11-32-14-19/h7-8,11-12,14,22-24,26-27,36H,9-10,13,15H2,1-6H3/t22-,23+,24+,26+,27-,29+,30+,31-/m1/s1
InChi Key: PMMQOFWSZRQWEV-RVTXXDJVSA-N
