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Product Description
A cell-permeable inhibitor of Akt activation without affecting the activation of the upstream kinase PDK1 or other kinases downstream of Ras such as MAPK. Induces apoptosis and kills a variety of cancer cell lines containing high levels of active Akt.
SH-5 is a cell-permeable inhibitor of Akt activation without affecting the activation of the upstream kinase PDK1 or other kinases downstream of Ras such as MAPK. Induces apoptosis and kills a variety of cancer cell lines containing high levels of active Akt.
Biovision | 1818 | SH-5 DataSheet
Alternate Name/Synonyms: D-3-Deoxy-2-O-methyl-myo-inositol 1-[(R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 701976-54-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₉H₅₉O₁₀P
Molecular Weight: 598.75
Cell-Permeable?: Yes
Purity: ≥98%
Solubilities: DMSO (10 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: An Akt inhibitor
MDL Number: N/A
PubChem CID: 16760282
SMILES: CCCCCCCCCCCCCCCCCCOCC(COP(=O)(O)OC1C(CC(C(C1O)O)O)OC)OC
InChi: InChI=1S/C29H59O10P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-37-22-24(35-2)23-38-40(33,34)39-29-26(36-3)21-25(30)27(31)28(29)32/h24-32H,4-23H2,1-3H3,(H,33,34)/t24-,25?,26?,27?,28?,29?/m1/s1
InChi Key: NRLLDDPUQZQEDV-UXPKSZKYSA-N
