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Product Description
An anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release , stimulates the insulin release and lowers blood glucose.
Sitagliptin Phosphate Monohydrate is an anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release , stimulates the insulin release and lowers blood glucose.
Biovision | 1757 | Sitagliptin Phosphate Monohydrate DataSheet
Alternate Name/Synonyms: 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate; MK-0431
Appearance: White solid
Formulation: N/A
CAS Number: 654671-77-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₁₅F₆N₅O•H₃PO₄•H₂O
Molecular Weight: 523.32
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: H₂O
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A DPP4 inhibitor
MDL Number: MFCD10001393
PubChem CID: 11591741
SMILES: C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)CC(CC3=CC(=C(C=C3F)F)F)N.O.OP(=O)(O)O
InChi: InChI=1S/C16H15F6N5O.H3O4P.H2O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22;1-5(2,3)4;/h4,6,9H,1-3,5,7,23H2;(H3,1,2,3,4);1H2/t9-;;/m1../s1
InChi Key: GQPYTJVDPQTBQC-KLQYNRQASA-N
