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Product Description
SMER-3 (Small molecule enhancer of rapamycin -3) is a selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo. Induces the expression of MET genes that results in cell cycle arrest and blockage of cell proliferation.
SMER-3 (Small molecule enhancer of rapamycin -3) is a selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo. Induces the expression of MET genes that results in cell cycle arrest and blockage of cell proliferation.
Biovision | 2514 | SMER-3 DataSheet
Alternate Name/Synonyms: 9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one
Appearance: Yellow solid
Formulation: N/A
CAS Number: 67200-34-4
Structure Available?: Yes
Peptide sequence: No
Salt Form: No
Molecular Formula: C₁₁H₄N₄O₂
Molecular Weight: 224.18
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>30 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: E3 Ubiquitin Ligase Inhibitor
MDL Number: MFCD00451458
PubChem CID: 568763
SMILES: C1=CC=C2C(=C1)C3=NC4=NON=C4N=C3C2=O
InChi: InChI=1S/C11H4N4O2/c16-9-6-4-2-1-3-5(6)7-8(9)13-11-10(12-7)14-17-15-11/h1-4H
InChi Key: SFSSAKVWCKFRHE-UHFFFAOYSA-N
