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Product Description
Sodium tanshinone IIA sulphonate (T06) is a water-soluble derivative of tanshinone IIA, that displays versatile biological properties. Recently, it has been shown to act as an ectosteric inhibitor of cathepsin K (CatK). T06 binds in an ectosteric side of Cathepsin K remote from its active site and selectively inhibits collagen degradation. It also inhibits bone resorption in ovariectomized mice.
Sodium tanshinone IIA sulphonate (T06) is a water-soluble derivative of tanshinone IIA, that displays versatile biological properties. Recently, it has been shown to act as an ectosteric inhibitor of cathepsin K (CatK). T06 binds in an ectosteric side of Cathepsin K remote from its active site and selectively inhibits collagen degradation. It also inhibits bone resorption in ovariectomized mice.
Biovision | B1902 | Tanshinone IIA-Sulfonic Sodium DataSheet
Alternate Name/Synonyms: Sodium tanshinone IIA sulfonate; Sulfotanshinone sodium II-A; T06
Appearance: Off-white to orange red powder
Formulation: N/A
CAS Number: 69659-80-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₉H₁₇NaO₆S
Molecular Weight: 396.39
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO or H₂O (~5 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent ectosteric inhibitor of cathepsin K (CatK)
MDL Number: MFCD09028094
PubChem CID: 23669322
SMILES: CC1=C(OC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C)S(=O)(=O)[O-].[Na+]
InChi: InChI=1S/C19H18O6S.Na/c1-9-13-15(20)16(21)14-10-5-4-8-19(2,3)12(10)7-6-11(14)17(13)25-18(9)26(22,23)24;/h6-7H,4-5,8H2,1-3H3,(H,22,23,24);/q;+1/p-1
InChi Key: AZEZEAABTDXEHR-UHFFFAOYSA-M
