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Product Description
Tobramycin is an aminoglycoside antibiotic that binds irreversibly to one of two aminoglycoside binding sites on the 30S ribosomal subunit, inhibiting bacterial protein synthesis. Tobramycin may also destabilize bacterial membranes by binding to 16S rRNA (ribosomal RNA). It inhibits translocation and elicits miscoding. Tobramycin is used to treat Pseudomonas aeruginosa lung infections and is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, sepsis, respiratory infections, osteomyelitis, and other soft-tissue infections.
Tobramycin is an aminoglycoside antibiotic that binds irreversibly to one of two aminoglycoside binding sites on the 30S ribosomal subunit, inhibiting bacterial protein synthesis. Tobramycin may also destabilize bacterial membranes by binding to 16S rRNA (ribosomal RNA). It inhibits translocation and elicits miscoding.
Biovision | B1537 | Tobramycin DataSheet
Alternate Name/Synonyms: O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1-6)-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1-4)]-2-deoxy-D-streptamine
Appearance: White solid
Formulation: N/A
CAS Number: 32986-56-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₁₈H₃₇N₅O₉
Molecular Weight: 467.52
Cell-Permeable?: Yes
Purity: ≥94%(Titration)
Solubilities: H₂O (>45 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: An aminoglycoside antibiotic
MDL Number: MFCD00077885
PubChem CID: 36294
SMILES: C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(CC(C(O3)CN)O)N)N
InChi: InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1
InChi Key: NLVFBUXFDBBNBW-PBSUHMDJSA-N
![Synthetic Tobramycin [OVA]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/451426/654559/images__81618.1648113406__74419.1648114774.png?c=2 "Synthetic Tobramycin [OVA]")
