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Product Description
U-18666A is a cell-permeable cholesterol trafficking inhibitor. It inhibits cholesterol transport from late endosomes/lysosomes to the endoplasmic reticulum (ER), but not cholesterol transport to the plasma membrane as demonstrated in many cell types including macrophages, primary cortical neurons and primary fibroblasts.
U-18666A is a cell-permeable cholesterol trafficking inhibitor. It inhibits cholesterol transport from late endosomes/lysosomes to the endoplasmic reticulum (ER), but not cholesterol transport to the plasma membrane as demonstrated in many cell types including macrophages, primary cortical neurons and primary fibroblasts.
Biovision | 9469 | U-18666A DataSheet
Alternate Name/Synonyms: (3β)-3-[2-(Diethylamino)ethoxy]androst-5-en-17-one hydrochloride
Appearance: White solid
Formulation: N/A
CAS Number: 3039-71-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₂₅H₄₁F₂NO₂.HCl
Molecular Weight: 424.07
Cell-Permeable?: Yes
Purity: ≥95%
Solubilities: H₂O (>30 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A cell-permeable cholesterol trafficking inhibitor.
MDL Number: MFCD00210908
PubChem CID: 9954082
SMILES: CCN(CC)CCOC1CCC2(C3CCC4(C(C3CC=C2C1)CCC4=O)C)C.Cl
InChi: nChI=1S/C25H41NO2.ClH/c1-5-26(6-2)15-16-28-19-11-13-24(3)18(17-19)7-8-20-21-9-10-23(27)25(21,4)14-12-22(20)24;/h7,19-22H,5-6,8-17H2,1-4H3;1H/t19-,20-,21-,22-,24-,25-;/m0./s1
InChi Key: GZFYZYBWLCYBMI-MYZJJQSMSA-N
