Product Description
Verteporfin is a photosensitizer used during photodynamic therapy to eliminate abnormal blood vessels in the eye that are associated with conditions such as macular degeneration. More recently, Verteporfin has been identified as an inhibitor of YAP-TEAD interaction. Also suppresses cancer stem cell properties in vitro.
Verteporfin is a photosensitizer used during photodynamic therapy to eliminate abnormal blood vessels in the eye that are associated with conditions such as macular degeneration. More recently, Verteporfin has been identified as an inhibitor of YAP-TEAD interaction. Also suppresses cancer stem cell properties in vitro.
Biovision | B1583 | Verteporfin DataSheet
Alternate Name/Synonyms: 4R,4aS)-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoic acid monomethyl ester; BPD-MA
Appearance: Black solid
Formulation: N/A
CAS Number: 129497-78-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₄₁H₄₂N₄O₈
Molecular Weight: 718.79
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>10 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A photosensitizer and cancer stem cell inhibitor
MDL Number: N/A
PubChem CID: 5362420
SMILES: CC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5C6(C(C(=CC=C6C(=N5)C=C1N2)C(=O)OC)C(=O)OC)C)C)CCC(=O)OC)C(=C3C)CCC(=O)O)C=C
InChi: InChI=1S/C41H42N4O8/c1-9-23-20(2)29-17-34-27-13-10-26(39(49)52-7)38(40(50)53-8)41(27,5)35(45-34)19-30-22(4)25(12-15-37(48)51-6)33(44-30)18-32-24(11-14-36(46)47)21(3)28(43-32)16-31(23)42-29/h9-10,13,16-19,38,42,44H,1,11-12,14-15H2,2-8H3,(H,46,47)/t38-,41+/m0/s1
InChi Key: YTZALCGQUPRCGW-ZSFNYQMMSA-N