Product Description
Cell-permeable. A selective inhibitor of cGMP-specific phosphodiesterase (PDE V) (IC₅₀ = 0.45 µM). Inhibits PDE IX only at higher concentrations (IC₅₀ = 35 µM).
Zaprinast is a selective inhibitor of cGMP-specific phosphodiesterase (PDE V) (IC₅₀ = 0.45 µM). Inhibits PDE IX only at higher concentrations (IC₅₀ = 35 µM).
Biovision | 1715 | Zaprinast DataSheet
Alternate Name/Synonyms: 1,4-Dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo(4,5-d)pyrimidin-7-one; M&B 22948
Appearance: White solid
Formulation: N/A
CAS Number: 37762-06-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₃H₁₃N₅O₂
Molecular Weight: 271.27
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (100 mM)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A PDE V inhibitor
MDL Number: MFCD00214073
PubChem CID: 5722
SMILES: CCCOC1=CC=CC=C1C2=NC(=O)C3=NNNC3=N2
InChi: InChI=1S/C13H13N5O2/c1-2-7-20-9-6-4-3-5-8(9)11-14-12-10(13(19)15-11)16-18-17-12/h3-6H,2,7H2,1H3,(H2,14,15,16,17,18,19)
InChi Key: REZGGXNDEMKIQB-UHFFFAOYSA-N