Product Description
Lipoxygenases are non-heme iron-containing dioxygenases. These enzymes convert unsaturated fatty acids to epoxides, such as leukotrienes from arachidonic acid. They play an important role in cell proliferation, differentiation and inflammation; and have been implicated in inflammation and hyper proliferation mediated diseases like asthma, rheumatoid arthritis and cancer.
Biovision | P1373 | 5-Lipoxygenase Active Human Recombinant DataSheet
Biomolecule/Target: 5-Lipoxygenase
Synonyms: ALOX5, 5-LOX, Arachidonate 5-lipoxygenase
Alternates names: ALOX5, 5-LOX, Arachidonate 5-lipoxygenase
Taglines: Non-heme iron-containing dioxygenases
NCBI Gene ID #: 240
NCBI Gene Symbol: ALOX5
Gene Source: Human
Accession #: P09917
Recombinant: TRUE
Source: E. coli
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): 300 µU/mg. The enzymes activity was assayed using BioVisions Lipoxygenase Activity Assay Kit (Catalog Number: K978).
Biological activity: N/A
Results: 300 µU/mg
Binding Capacity: N/A
Unit Definition: One unit is the amount of enzyme that will hydrolyze 1.0 µmole of arachidonic acid at pH 7.4 and 25 C.
Molecular Weight: 68.3 kDa (1-579 aa + N-terminal His Tag)
Concentration: N/A
Appearance: Liquid
Physical form description: Liquid
Reconstitution Instructions: N/A
Amino acid sequence: 1-579 aa