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Product Description
AKT1 Human, Protein Kinase B Alpha Human Recombinant Protein, Sf9
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Size 10ug
Background AKT56.7kDa. (Molecular size on SDS-PAGE will appear atapproximately 50-70kDa).AKT1 is expressed with an 8 amino acid His tag atC-Terminus and purified by proprietary chromatographic techniques.
Source Sf9,Baculovirus cells.
Gene name AKT1
Contents AKT1 protein solution (0. 5mg/ml) contains phosphate buffered saline (pH7.4) and 20% glycerol.
Form Sterile filtered colorless solution.
Purification Greater than 90.0% as determined by SDS-PAGE.
Storage Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Application Cell Culture
Synonyms RAC-alpha serine/threonine-protein kinase;2.7.11.1;Protein kinase B;PKB;Protein kinase B alpha;PKB alpha;Proto-oncogene c-Akt;RAC-PK-alpha;AKT1;PKB, RAC;
Subcellular localization Cytoplasm. Nucleus. Cell membrane. Nucleus after activation by integrin-linked protein kinase 1 (ILK1). Nuclear translocation is enhanced by interaction with TCL1A. Phosphorylation on Tyr-176 by TNK2 results in its localization to the cell membrane w
Tissue specificity Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancer
Uniprot ID P31749
Other Size 2ug, 10ug, 1mg, Please contact us for more details
