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Product Description
BrdT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence. The bromodomain is found in proteins that regulate transcription. BrdT drives a meiotic and post-meiotic gene expression program. It also controls the genome-wide post-meiotic genome reorganization that occurs after histone hyperacetylation in elongating spermatids. It may play a role in the transcriptional regulation of spermatogenesis. It also seems to have a structural ATP-independent role in the reorganization of acetylated chromatin. BioVisions recombinant protein includes Bromo 1 domain (257-382 aa) with N-terminal His-tag.
Biomolecule/Target: BRDT
Synonyms: Recombinant Human Bromodomain Testis-specific Protein (BrdT)
Alternates names: BCMA, CD269, Tumor Necrosis Factor Receptor Superfamily Member 17, BCM, TNFRSF17, B-cell maturation protein, CD269 antigen.
Taglines: A protein involved in chromatin targeting
NCBI Gene ID #: 608
NCBI Gene Symbol: TNR17
Gene Source: Human
Accession #: Q02223
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 5.3 kDa
Concentration: N/A
Appearance: Liquid
Physical form description: rh-BrdT is supplied as a solution in 50 mM Tris, pH 8.0, 150 mM NaCl and 10% Glycerol.
Reconstitution Instructions: It is recommended to reconstitute the lyophilized BCMA in sterile dHO not less than 100 g/ml, which can then be further diluted to other aqueous solutions.
Amino acid sequence: N/A
