Product Description
Human Betacellulin (BTC) is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. The effects of betacellulin are probably mediated by the egf receptor and other related receptors. Human Recombinant BTC produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 80 amino acids and having a molecular mass of 9 kDa. BTC was purified by proprietary chromatographic techniques.
Biovision | 4876 | BTC human recombinant DataSheet
Biomolecule/Target: N/A
Synonyms: Betacellulin, BTC
Alternates names: Beta-defensin 3, Defensin, beta 103, Defensin-like protein, DEFB103A, BD3, DEFB103, DEFB3, DEFB103B
Taglines: A ligand for the EGF receptor
NCBI Gene ID #: 140596
NCBI Gene Symbol: DEFB4
Gene Source: Human
Accession #: Q8WTQ1
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: 97%
Assay #2: HPLC
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: Determined by its ability to chemoattract human monocytes using a concentration range of 0.1-50 ng/ml.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: ~6.0 kDa
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Lyophilized after extensive dialysis against 20 mM phosphate buffer, pH 7.4.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile dd HO to a concentration 100 µg/ml. This solution can then be diluted into other aqueous buffers and stored at 4 °C for 2-7 days and at -20 °C for future use.
Amino acid sequence: N/A