Euro
USD
British Pound
NULL
Product Description
T-cell surface glycoprotein CD3 zeta chain, also known as CD247, belongs to the CD3Z/FCER1G family. CD247 is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Recombinant human CD247 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Biovision | 7340 | CD247 human recombinant DataSheet
Biomolecule/Target: CD247
Synonyms: T-cell surface glycoprotein CD3 zeta chain, CD3-ZETA, CD3H, CD3Q, CD3Z, T3Z, TCRZ
Alternates names: T-cell surface glycoprotein CD3 zeta chain, CD3-ZETA, CD3H, CD3Q, CD3Z, T3Z, TCRZ
Taglines: Plays a role in coupling antigen recognition to several intracellular signal-transduction pathways
NCBI Gene ID #: 20305
NCBI Gene Symbol: CCL6
Gene Source: Human
Accession #: P27784
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 97%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 15.4 kDa (136 aa, 52-164 aa + His Tag), confirmed by MALDI-TOF.
Concentration: 0.5 mg/ml
Appearance: Liquid
Physical form description: 0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol and 1 mM DTT.
Reconstitution Instructions: N/A
Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MGSRVKFSRS ADAPAYQQGQ NQLYNELNLG RREEYDVLDK RRGRDPEMGG KPQRRKNPQE GLYNELQKDK MAEAYSEIGM KGERRRGKGH DGLYQGLSTA TKDTYDALHM QALPPR
