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Product Description
FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse fused toes mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.
Biovision | 7558 | FTO mouse recombinant DataSheet
Biomolecule/Target: FTO
Synonyms: Fat Mass and Obesity-associated Protein; FATSO.
Alternates names: Fat Mass and Obesity-associated Protein; FATSO.
Taglines: The gene responsible for mouse fused toes mutation.
NCBI Gene ID #: 2253
NCBI Gene Symbol: FGF8
Gene Source: Mouse
Accession #: P55076
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: <1 EU/g by LAL method
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: ~55 kDa (SDS-PAGE). Mouse FTO (aa 2-502) is fused at the N-terminus to a His-tag.
Concentration: 0.5 mg/ml
Appearance: Liquid
Physical form description: 0.5 mg/ml of 0.2 m-filtered solution in 55 mM Tris-Cl, pH 8.2 containing 150 mM NaCl.
Reconstitution Instructions: N/A
Amino acid sequence: N/A
