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Product Description
Gremlin (also known as Increased in High Glucose Protein 2, IHG-2, Down-regulated in Mos-transformed cells protein, Drm) functions as a bone morphogenetic protein (BMP) antagonist. It acts by binding to, and forming heterodimers with BMP-2, BMP-4, BMP-7, thus preventing them from interacting with their cell surface receptors. Recombinant human Gremlin-2 is a N-terminus His-tagged protein that was expressed from E. coli.
Biovision | 4657 | Gremlin 2 human recombinant DataSheet
Biomolecule/Target: N/A
Synonyms: Gremlin 2
Alternates names: FST, FS, Activin-binding protein
Taglines: Inhibitor of BMP-2, -4, and -7
NCBI Gene ID #: 10468
NCBI Gene Symbol: FST
Gene Source: Human
Accession #: P19883
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: 95%
Assay #2: HPLC
Endotoxin Level: <0.1 ng/g
Activity (Specifications/test method): N/A
Biological activity: Determined by its ability to neutralize Activin A inhibitory effect of murine MPC-11 cells. The expected ED is 0.1-0.4 µg/ml in the presence of 7.5 ng/ml Activin A.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 31.5 kDa
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Sterile filtered and lyophilized with no additives
Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 µg/µl. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or 20°C for future use.
Amino acid sequence: N/A
