Product Description
AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. AKT regulates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', resulting in inhibition of its kinase activity.
Biovision | 7886 | Human CellExp Akt1 Protein His Tagged & Strep Tagged human recombinant DataSheet
Biomolecule/Target: Akt1
Synonyms: RAC-alpha serine/threonine-protein kinase, AKT1, PKB, RAC, RAC-PK-alpha, PKB alpha, Proto-oncogene cAkt
Alternates names: APS, KLK2A1, PSA, Hk3, P-30 antigen, SemenoGelase
Taglines: One of 3 serine/threonine-protein kinases that regulate many process including metabolism, proliferation, cell survival, growth and angiogenesis.
NCBI Gene ID #: 354
NCBI Gene Symbol: KLK3
Gene Source: Human
Accession #: P07288
Recombinant: Yes
Source: HEK293 cells
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: Measured by its ability to cleave the colorimetric peptide substrate, Succinyl-Arg-Pro-Tyr-p-Nitroanilide (Suc-RPY-pNA). The specific activity is >100 pmoles/min/g
Results: >100 pmoles/min/g
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 35 kDa
Concentration: N/A
Appearance: Dry powder
Physical form description: Lyophilized powder
Reconstitution Instructions: Detailed reconstitution instructions are sent along with the product.
Amino acid sequence: N/A