Euro
USD
British Pound
NULL
Product Description
BMP2 belongs to the transforming growth factor-beta (TGF) superfamily. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. In addition to its osteogenic activity, BMP-2 also plays an important role in cardiac morphogenesis. BMP-2 is expressed in a variety of tissues such as lung, spleen, brain, liver, prostate ovary, and small intestine. BMP2 is a candidate gene for the autosomal dominant disease of fibrodysplasia (myositis) ossificans progressiva. BioVisions BMP-2 is produced in a serum-free, chemically defined media. Production in human 293 cells offers authentic glycosylation, contributing to stability in cell growth media and other applications.
Biovision | 6444 | Human CellExp BMP-2 Human Recombinant DataSheet
Biomolecule/Target: N/A
Synonyms: Human Cellexp Human Recombinant BMP-2
Alternates names: Proepithelin; PEPI; PC Cell-derived Growth Factor
Taglines: A protein involved in the hedgehog and TGF beta signaling pathway
NCBI Gene ID #: 10116
NCBI Gene Symbol: GRN
Gene Source: Human
Accession #: P23785
Recombinant: Yes
Source: Human 293 cell expressed
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per 1 g of protein
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: ~65.0 kDa
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from a solution of 50 mM sodium acetate, pH 4.5, with 50 mM NaCl.
Reconstitution Instructions: Reconstitute in dH2O before use.
Amino acid sequence: Signal peptide and rat Progranulin (aa 1-602) fused at the C-terminus to a FLAG®-tag.
