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Product Description
Interleukin-2 (IL-2) is a potent immuno-modulator, which mediates a wide range of immune and inflammatory responses and is important for the proliferation of T and B lymphocytes. IL-2 is one of the key cytokines for the immune system, tolerance and immunity. It has been approved for the treatment of metastatic renal cell carcinoma and metastatic melanoma in cancer immunotherapy with long term disease control. In addition to being used as monotherapy, IL-2 can also be combined with other anticancer immunotherapies, such as adoptive cell transfer, vaccination, and blockade of immune checkpoint inhibitory molecules, such as cytotoxic T lymphocyte-associated antigen 4 and programmed death 1 monoclonal-antibodies as a promising treatment for metastatic cancer.
Biovision | P1385 | Human CellExpIL-2 Human Recombinant DataSheet
Biomolecule/Target: N/A
Synonyms: T-cell growth factor (TCGF), Aldesleukin, Lymphokine, IL-2.
Alternates names: Peroxiredoxin 6, 1-Cys, aiPLA2, AOP2, NSGPx, p29, PRX.
Taglines: A regulator of lymphocyte activities
NCBI Gene ID #: 9588
NCBI Gene Symbol: PRDX6
Gene Source: Human
Accession #: P30041
Recombinant: FALSE
Source: E. coli
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: Specific activity: approximately 95-120 pmole/min/µg.
Results:
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 27.1 kDa
Concentration: N/A
Appearance: Lyophilized powder
Physical form description: Lyophilized
Reconstitution Instructions: N/A
Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MPGGLLLGDV APNFEANTTV GRIRFHDFLG DSWGILFSHP RDFTPVCTTE LGRAAKLAPE FAKRNVKLIA LSIDSVEDHL AWSKDINAYN CEEPTEKLPF PIIDDRNREL AILLGMLDPA EKDEKGMPVT ARVVFVFGPD KKLKLSILYP ATTGRNFDEI LRVVISLQLT AEKRVATPVD WKDGDSVMVL PTIPEEEAKK LFPKGVFTKE LPSGKKYLRY TPQP
