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Product Description
Cyclophilin H is a member of peptidyl-propyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. The cyclophilin H is a specific component of the human U4/U6 small nuclear ribonucleoprotein particle involved in the nuclear splicing of pre-mRNA. It stably associates with the U4/U6-60kD and -90kD proteins, the human orthologues of the Saccharomyces cerevisiae Prp4 and Prp3 splicing factors.
Biovision | 6313 | Human Recombinant Cyclophilin H DataSheet
Biomolecule/Target: N/A
Synonyms: Human Recombinant Cyclophilin H
Alternates names: Peptidylprolyl isomerase H, CYPH, CYP20, SnuCyp-20, PPIase H, Rotamase H
Taglines: An immunophilin family protein catalyzing the isomerization of peptide bonds
NCBI Gene ID #: 3592
NCBI Gene Symbol: IL12
Gene Source: Human
Accession #: P29459
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per 1 g of protein (determined by LAL method)
Activity (Specifications/test method): N/A
Biological activity: Specific activity is > 220 nmoles/min/mg
Results: N/A
Binding Capacity: N/A
Unit Definition: Specific activity is defined as the amount of enzyme that cleaves 1 µmole of Suc-AAFP-pNA per minute at 25°C in Tris HCl pH 8.0 using chymotrypsin.
Molecular Weight: 19.2 kDa
Concentration: 1 mg/ml
Appearance: Liquid
Physical form description: 1 mg/ml solution in PBS (pH 7.4) containing 10% glycerol.
Reconstitution Instructions: N/A
Amino acid sequence: MAVANSSPVN PVVFFDVSIG GQEVGRMKIE LFADVVPKTA ENFRQFCTGE FRKDGVPIGY KGSTFHRVIK DFMIQGGDFV NGDGTGVASI YRGPFADENF KLRHSAPGLL SMANSGPSTN GCQFFITCSK CDWLDGKHVV FGKIIDGLLV MRKIENVPTG PNNKPKLPVV ISQCGEM
