Product Description
Ubiquitin-conjugating enzyme E2 (UBE2E2) is a protein that in humans is encoded by the UBE2E2 gene. Amino acid sequence within the UBC domain of UBE2E2 shares over 90% identity with human UbcH6, mouse UbcM2, and Drosophila UbcD2, whereas the N-terminal region shows little amino acid sequence similarity with known proteins. The UBE2E2 protein forms a thioester bond with ubiquitin in an E1-dependent manner and mediates the transfer of ubiquitin from a ubiquitin-activating enzyme (E1) to a substrate protein or E3 ligase.
Biovision | 6438 | Human recombinant UBE2E2 UbcH8 DataSheet
Biomolecule/Target: N/A
Synonyms: Human recombinant UBE2E2 (UbcH8)
Alternates names: RIG-B, UBCH8, MGC40331, UBE2L6, Ubiquitin/ISG15-conjugating enzyme E2 L6, Ubiquitin-protein ligase L6, Ubiquitin carrier protein L6, and Retinoic acid-induced gene B protein.
Taglines: Ubiquitin conjugating enzyme involved in conjugation of ubiquitin to target substrates.
NCBI Gene ID #: 60505
NCBI Gene Symbol: IL21
Gene Source: Human
Accession #: Q9ES17
Recombinant: Yes
Source: N/A
Purity by SDS-PAGEs: 95%
Assay: RP-HPLC
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: Protein concentration of 100 nM - 1 µM is recommended for in vitro conjugation.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 22.255 kDa
Concentration: N/A
Appearance: Liquid
Physical form description: 75 µL of a 40 µM solution (3 nmoles) in 20 mM Tris, pH 7.4, 150 mM NaCl, 10 mM DTT and 10% glycerol.
Reconstitution Instructions: N/A
Amino acid sequence: N/A