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Product Description
IFN- is a type I interferon, which can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-, IFN-, and IFN-, signal through IFNAR-1/IFNAR-2 receptor complex, and exert antiviral and antiproliferative activities. IFN- exhibits about 75% sequence homology with IFN-, and contains two conserved disulfide bonds, which are necessary for full biological activity. Recombinant Human IFN- is a 19.9 kDa protein consisting of 172 amino acid residues.
Biovision | 7164 | IFN- human recombinant DataSheet
Biomolecule/Target: IFN-
Synonyms: IFN alpha II-1, IFNW1
Alternates names: Peptidyl-prolyl cis-trans isomerase FKBP14, FKBP22
Taglines: Exerts antiviral and antiproliferative activities
NCBI Gene ID #: 55033
NCBI Gene Symbol: FKBP14
Gene Source: Human
Accession #: Q9NWM8
Recombinant: Yes
Source: E. Coli
Purity by SDS-PAGEs: 90%
Assay: SDS-PAGE
Purity: N/A
Assay #2: HPLC
Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).
Activity (Specifications/test method): N/A
Biological activity: Specific activity is > 240 nmoles/min/mg, and is defined as the amount of enzyme that cleaves 1 µmole of Suc-AAFP-pNA per minute at 25°C in Tris HCl pH 8.0 using chymotrypsin.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 24.2 kDa (213 aa, 20-211 aa + NT His Tag)
Concentration: N/A
Appearance: Lyophilized powder
Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.
Reconstitution Instructions: N/A
Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MALIPEPEVK IEVLQKPFIC HRKTKGGDLM LVHYEGYLEK DGSLFHSTHK HNNGQPIWFT LGILEALKGW DQGLKGMCVG EKRKLIIPPA LGYGKEGKGK IPPESTLIFN IDLLEIRNGP RSHESFQEMD LNDDWKLSKD EVKAYLKKEF EKHGAVVNES HHDALVEDIF DKEDEDKDGF ISAREFTYKH DEL
