Product Description
Galectin-8, also known as prostate-specific membrane antigen (PCTA1), is an additional prostate-specific antigen that is overexpressed only in malignant tumors and therefore is a more specific identifier of malignancies. It is a member of the galectin gene family which mediates both cell-cell and cell matrix interactions in a manner similar to the selectin subgroup of C-type lectins. Recombinant mouse Galectin-8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Biovision | 7366 | LGALS8 mouse recombinant DataSheet
Biomolecule/Target: LGALS8
Synonyms: Lectin, galactose binding, soluble 8; LGALS8
Alternates names: Lectin, galactose binding, soluble 8; LGALS8
Taglines: A specific identifier of malignant tissues.
NCBI Gene ID #: 287561
NCBI Gene Symbol: MCP3
Gene Source: Mouse
Accession #: Q9QXY8
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 97%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: The activity is determined by the ability to chemoattract human monocytes or THP-1 cells at 1-100 ng/mL.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 38 kDa (339 aa, 1-316 aa + His Tag).
Concentration: 0.5 mg/ml
Appearance: Liquid
Physical form description: 0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 0.15 M NaCl and 20% glycerol.
Reconstitution Instructions: When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/mL, which can be further diluted into other aqueous solutions.
Amino acid sequence: MQPDGTNSST CCYVKKQKIP KRNLKSYRKI TSSRCPWEAV IFKTKKGMEV CAEAHQKWVE EAIAYLDMKT STPKP