PARK2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 485 amino acids (1-465) and having a molecular mass of 53.8 kDa. PARK2 is fused to a 20 amino acid His-tag at N-terminus.
Source:
E. Coli
Gene name:
PARK2
Contents:
The PARK2 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Form:
Sterile Filtered clear solution.
Purification:
Greater than 80% as determined by SDS-PAGE.
Storage:
Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Application:
Cell Culture
Synonyms:
E3 ubiquitin-protein ligase parkin;Parkin;6.3.2.-;Parkinson juvenile disease protein 2;Parkinson disease protein 2;PARK2;PRKN;
Subcellular localization:
Cytoplasm, cytosol
Tissue specificity:
Highly expressed in the brain including the substantia nigra. Expressed in heart, testis and skeletal muscle. Expression is down-regulated or absent in tumor biopsies, and absent in the brain of PARK2 patients. Overexpression protects dopamine neuron
Uniprot ID:
O60260
Other Size:
5ug, 20ug, 1mg, Please contact us for more details
PARK2 Parkinson Disease Protein 2 Human Recombinant Protein
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BackgroundPARK2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 485 amino acids (1-465) and having a molecular mass of 53.8 kDa. PARK2 is fused to a 20 amino acid His-tag at N-terminus.
PurificationGreater than 80% as determined by SDS-PAGE.
StorageStore in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
ApplicationCell Culture
SynonymsE3 ubiquitin-protein ligase parkin;Parkin;6.3.2.-;Parkinson juvenile disease protein 2;Parkinson disease protein 2;PARK2;PRKN;
Subcellular localizationCytoplasm, cytosol
Tissue specificityHighly expressed in the brain including the substantia nigra. Expressed in heart, testis and skeletal muscle. Expression is down-regulated or absent in tumor biopsies, and absent in the brain of PARK2 patients. Overexpression protects dopamine neuron
Uniprot IDO60260
Other Size5ug, 20ug, 1mg, Please contact us for more details