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Product Description
PKAkt1/PKBa Protein Kinase Akt1/PKB alpha, Active enzyme Human Recombinant Protein
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Size 20ug
Background Recombinant Human Protein Kinase B is a glycosylated polypeptide having a molecular mass of 59.1 kDa.
Recombinant Protein Kinase B is purified by proprietary chromatographic techniques.
Recombinant Protein Kinase B is purified by proprietary chromatographic techniques.
Source Sf9 insect cells.
Gene name AKT1
Contents PKAkt1 1.9mg/ml, in 50mM NaCl, 1mM DTT, 25mM beta glycerophosphate, 50% glycerol, pH 8.5.
Form Sterile Filtered clear solution.
Purification Greater than 90% as determined by SDS-PAGE.
Storage Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Application Cell Culture
Synonyms RAC-alpha serine/threonine-protein kinase;2.7.11.1;Protein kinase B;PKB;Protein kinase B alpha;PKB alpha;Proto-oncogene c-Akt;RAC-PK-alpha;AKT1;PKB, RAC;
Subcellular localization Cytoplasm. Nucleus. Cell membrane. Nucleus after activation by integrin-linked protein kinase 1 (ILK1). Nuclear translocation is enhanced by interaction with TCL1A. Phosphorylation on Tyr-176 by TNK2 results in its localization to the cell membrane w
Tissue specificity Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancer
Uniprot ID P31749
Other Size 5ug, 20ug, 40ug, Please contact us for more details
