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Product Description
PLGF (also called Placenta Growth Factor, PIGF, PGF) is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PLGF is expressed in placental tissues, colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. Recombinant mouse PLGF is a disulfide-linked homodimer containing two 142 amino acid polypeptide chains.
Biovision | 4739 | PLGF-1 human recombinant DataSheet
Biomolecule/Target: N/A
Synonyms: PIGF, PGF, PLGF 1, Placenta Growth Factor-1
Alternates names: IL-1F, IL-1 (epsilon), IL-1F9, IL-1H1
Taglines: A key molecule in angiogenesis and vasculogenesis
NCBI Gene ID #: 56300
NCBI Gene Symbol: IL36G
Gene Source: Human
Accession #: Q9NZH8
Recombinant: Yes
Source: E. coli.
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: HPLC
Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).
Activity (Specifications/test method): Measured by its ability to induce IL-8 production by human PBMCs
Biological activity: Measured by its ability to induce IL-8 production by human PBMCs
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 17.0 kDa
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Sodium Phosphate, pH 7.0 and 50 mM NaCl.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Amino acid sequence: SMCKPITGTI NDLNQQVWTL QGQNLVAVPR SDSVTPVTVA VITCKYPEAL EQGRGDPIYL GIQNPEMCLY CEKVGEQPTL QLKEQKIMDL YGQPEPVKPF LFYRAKTGRT STLESVAFPD WFIASSKRDQ PIILTSELGK SYNTAFELNI ND
