Product Description
Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed peroxisome proliferators activated receptors (PPARs). Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Studies indicate that PPARs are activated by peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643, as well as by some fatty acids.
Biovision | P1120 | PPARG Human Recombinant DataSheet
Biomolecule/Target: PPARG
Synonyms: Peroxisome proliferator-activated receptor gamma, PPAR-gamma, PPARG, NR1C3, PPARG1, PPARG2
Alternates names: Peroxisome proliferator-activated receptor gamma, PPAR-gamma, PPARG, NR1C3, PPARG1, PPARG2
Taglines: Recombinant Human PPAR can be used in the inhibition assays, western blotting, ELISA, and numerous such applications
NCBI Gene ID #: 8600
NCBI Gene Symbol: OPG
Gene Source: Human
Accession #: O14788
Recombinant: Yes
Source: E.coli
Purity by SDS-PAGEs: 98%
Assay: N/A
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: Determined by its ability to neutralize the stimulation of U937 cells treated with 10 ng/ml of sRANKL.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 80 kDa
Concentration: N/A
Appearance: Liquid
Physical form description: In 50 mM Tris-HCl and 10 mM L-glutathione (reduced).
Reconstitution Instructions: Reconstitute in 5 mM Tris, pH 7.5 to a concentration of 0.1-1.0 mg/ml. The solution can be diluted into other aqueous buffers and stored at 4°C for 1 week or 20°C for future use.
Amino acid sequence: N/A