IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical bi
Source:
E. Coli
Gene name:
IL1B
Contents:
Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
Form:
Solid; white powder or thin/invisible film
Purification:
N/A
Storage:
Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Cytoplasm, cytosol . Lysosome . Secreted, exosome . Secreted . The precursor is cytosolic. In response to inflammasome- activating signals, such as ATP for NLRP3 inflammasome or bacterial flagellin for NLRC4 inflammasome, cleaved and secreted. IL1B l
Tissue specificity:
Expressed in activated monocytes/macrophages (at protein level). .
BackgroundIL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical bi
SourceE. Coli
Gene nameIL1B
ContentsProtein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
FormSolid; white powder or thin/invisible film
PurificationN/A
StorageStore in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Subcellular localizationCytoplasm, cytosol . Lysosome . Secreted, exosome . Secreted . The precursor is cytosolic. In response to inflammasome- activating signals, such as ATP for NLRP3 inflammasome or bacterial flagellin for NLRC4 inflammasome, cleaved and secreted. IL1B l
Tissue specificityExpressed in activated monocytes/macrophages (at protein level). .
Uniprot IDP01584
Other SizeVarious Sizes, Please contact us for more details