LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating
Source:
Hi-5 Insect cells
Gene name:
TNFSF14
Contents:
Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
Form:
Solid; white powder or thin/invisible film
Purification:
N/A
Storage:
Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Application:
Cell Culture
Synonyms:
Tumor necrosis factor ligand superfamily member 14;Herpes virus entry mediator ligand;HVEM-L;Herpesvirus entry mediator ligand;CD258;Tumor necrosis factor ligand superfamily member 14, membrane form;Tumor necrosis factor ligand superfamily member 14,
Subcellular localization:
Tumor necrosis factor ligand superfamily member 14, membrane form: Cell membrane; Single-pass type II membrane protein.
Tissue specificity:
Predominantly expressed in the spleen but also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoiet
BackgroundLIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating
SourceHi-5 Insect cells
Gene nameTNFSF14
ContentsProtein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
FormSolid; white powder or thin/invisible film
PurificationN/A
StorageStore in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
ApplicationCell Culture
SynonymsTumor necrosis factor ligand superfamily member 14;Herpes virus entry mediator ligand;HVEM-L;Herpesvirus entry mediator ligand;CD258;Tumor necrosis factor ligand superfamily member 14, membrane form;Tumor necrosis factor ligand superfamily member 14,
Subcellular localizationTumor necrosis factor ligand superfamily member 14, membrane form: Cell membrane; Single-pass type II membrane protein.
Tissue specificityPredominantly expressed in the spleen but also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoiet
Uniprot IDO43557
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