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![Recombinant Human BD-1 (47aa) Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/670502/928345/logo__42078.1651665136__91404.1651684016.jpg?c=2 "Recombinant Human BD-1 (47aa) Protein [E. coli]"){kind=logo}
Product Description
Recombinant Human BD-1 (47aa) Protein [E. coli] | 100-133S/100-133 | ReliaTech
Species: Human
Host / biotech: E. coli
Comment: N/A
Label: N/A
Clone / Antibody feature: N/A
Subcategory: Cytokines & Growth Factors
Category: Recombinant Protein
Synonyms: DEFB1; BD1; HBD1; DEFB-1; DEFB101
Isotype: N/A
Application: N/A
Detection Range: Determined by its ability to chemoattract CD34+ dendritic cells using a concentration range of 100-1000 ng/ml.
Species Reactivity/Cross reactivity: Human
Antigen: N/A
Description: Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. Beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The Beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36 a.a.), a propeptide region. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Beta-Defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues. Recombinant Human BD-1 is a 5.0 kDa protein containing 47 amino acid residues.
Purity Confirmation: > 98% by SDS-PAGE & HPLC analyses
Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
Formulation: lyophilized
Storage Handling Stability: N/A
Reconstituation: N/A
Molecular Weight: 5.0 kDa
Lenght (aa): 47
Protein Sequence: GNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCK
NCBI Gene ID: 1672
![Recombinant Human BD-1 (47aa) Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/670502/928345/logo__42078.1651665136__91404.1651684016.jpg?c=2 "Recombinant Human BD-1 (47aa) Protein [E. coli]"){kind=logo}
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