Euro
USD
British Pound
NULL
![Recombinant Rat VEGF164 Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/672234/930077/logo__42078.1651665136__80870.1651684511.jpg?c=2 "Recombinant Rat VEGF164 Protein [E. coli]"){kind=logo}
![Recombinant Rat VEGF164 Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/672234/930077/logo__42078.1651665136__80870.1651684511.jpg?c=2 "Recombinant Rat VEGF164 Protein [E. coli]"){kind=logo}
Product Description
Recombinant Rat VEGF164 Protein [E. coli] | R20-067S/R20-067/R20-068 | ReliaTech
Species: Rat
Host / biotech: E. coli
Comment: N/A
Label: N/A
Clone / Antibody feature: N/A
Subcategory: Cytokines & Growth Factors
Category: Recombinant Protein
Synonyms: vascular endothelial growth factor A; Vegfa; Vegf; VEGF164
Isotype: N/A
Application: N/A
Detection Range: Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 2-10 ng/ml.
Species Reactivity/Cross reactivity: Rat
Antigen: N/A
Description: Rat Vascular Endothelial Growth Factor164 (VEGF164), a 19.23 kDa protein consisting of 164 amino acid residues, is produced as a homodimer. VEGF164 is a polypeptide growth factor and a member of the platelet-derived growth factor family. It is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. Two high-affinity tyrosine kinase receptors for VEGF164 have been identified, VEGFR-1 (FLT-1), and VEGFR-2 (Flk-1). Consistent with the endothelial cell-specific action of VEGF120, expression of both receptor genes has been found predominantly but not exclusively on endothelial cells. Expression of VEGFR-1 was also found on human monocytes, neutrophils (PMNs), bovine brain pericytes and villous and extravillous trophoblasts. In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo and is also a chemo attractant for monocytes and endothelial cells. At least four different proteins are generated by differential splicing of the mouse VEGF gene: VEGF120, VEGF144, VEGF164 and VEGF188. The most abundant form is VEGF164. Whereas VEGF120, VEGF144 and VEGF164 are secreted proteins, VEGF188 is strongly cell-associated. In addition, the isoforms VEGF164 and VEGF188 bind to heparin with high affinity. All dimeric forms possess similar biological activities. A related protein of VEGF is placenta growth factor (PlGF) with about 53% homology and VEGF-B with similar biological activities. The full ORF of native rat VEGF164 (Ala27-Arg190) was cloned from total RNA of rat sinusoidal endothelial cells using standard protocols
Purity Confirmation: > 95% by SDS-PAGE
Endotoxin: N/A
Formulation: lyophilized (freeze-dried)
Storage Handling Stability: Lyophilized samples are stable for greater than six months at -20°C to -70°C. Reconstituted VEGF164 should be stored in working aliquots at -20°C
Reconstituation: The lyophilized VEGF164 should be reconstituted in ddH2O to a concentration not lower than 50µg/ml.
Molecular Weight: 19.23 kDa
Lenght (aa): 164
Protein Sequence: APTTEGEQKSHEVIKFMDVYQRSYCRPIETLVDIFQEYPDEIEYIFKPSCVPLMRCAGCCNDEALECVPTSESNITMQIMRIKPHQSQHIGEMSFLQHSRCECRPKKDRTKPENHCEPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
NCBI Gene ID: 83785
![Recombinant Rat VEGF164 Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/672234/930077/logo__42078.1651665136__80870.1651684511.jpg?c=2 "Recombinant Rat VEGF164 Protein [E. coli]"){kind=logo}
![Recombinant Rat VEGF188 Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/672241/930084/logo__42078.1651665136__00506.1651684515.jpg?c=2 "Recombinant Rat VEGF188 Protein [E. coli]"){kind=logo}
![Recombinant Rat VEGF120 Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/672227/930070/logo__42078.1651665136__38973.1651684507.jpg?c=2 "Recombinant Rat VEGF120 Protein [E. coli]"){kind=logo}
![Recombinant Rat Prolactin Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671896/929739/logo__42078.1651665136__98903.1651684412.jpg?c=2 "Recombinant Rat Prolactin Protein [E. coli]"){kind=logo}
![Recombinant Rat TPO Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/672173/930016/logo__42078.1651665136__00781.1651684493.jpg?c=2 "Recombinant Rat TPO Protein [E. coli]"){kind=logo}
![Recombinant Rat CNTF Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/670733/928576/logo__42078.1651665136__59441.1651684074.jpg?c=2 "Recombinant Rat CNTF Protein [E. coli]"){kind=logo}