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Product Description
Rabbit Anti-Human OPG Antibody | 102-P200 | ReliaTech
Species: Anti-Human
Host / biotech: Rabbit
Comment: N/A
Label: N/A
Clone / Antibody feature: Rabbit IgG
Subcategory: Polyclonal Antibody
Category: Antibody
Synonyms: TNFRSF11B; OPG; TR1; OCIF
Isotype: N/A
Application: ELISA, WB
Detection Range: N/A
Species Reactivity/Cross reactivity: Human
Antigen: Recombinant Human OPG
Description: Osteoprotegerin (OPG) is a member of the TNFR superfamily that can act as a decoy receptor for RANKL. Binding of soluble OPG to sRANKL inhibits osteoclastogenesis by interrupting the signaling between stromal cells and osteoclastic progenitor cells, thereby leading to excess accumulation of bone and cartilage. OPG is expressed in a wide variety of tissues including adult heart, lung, kidney, liver, spleen, prostate, lymph node and bone marrow. OPG is secreted both as a monomeric and a dimeric protein. Its primary structure consists of seven distinct domains, four of which corresponds to the extracellular cysteine-rich domains of TNFR proteins and constitutes the soluble OPG. Recombinant human OPG is a soluble 20.0 kDa protein containing 174 amino acid residues.
Purity Confirmation: N/A
Endotoxin: N/A
Formulation: lyophilized from PBS
Storage Handling Stability: The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Reconstituation: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Molecular Weight: N/A
Lenght (aa): N/A
Protein Sequence: N/A
NCBI Gene ID: 4982
