Euro
USD
British Pound
NULL
Product Description
Rabbit Anti-Human TIMP-1 Antibody | 102-P252 | ReliaTech
Species: Anti-Human
Host / biotech: Rabbit
Comment: N/A
Label: N/A
Clone / Antibody feature: Rabbit IgG
Subcategory: Polyclonal Antibody
Category: Antibody
Synonyms: TIMP1; EPA; EPO; HCI; CLGI; TIMP
Isotype: N/A
Application: ELISA, WB
Detection Range: N/A
Species Reactivity/Cross reactivity: Human
Antigen: recombinant human TIMP-1
Description: TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.
Purity Confirmation: N/A
Endotoxin: N/A
Formulation: lyophilized from PBS
Storage Handling Stability: The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Reconstituation: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Molecular Weight: N/A
Lenght (aa): N/A
Protein Sequence: N/A
NCBI Gene ID: 7076
