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Product Description
Rat Anti-Mouse Lyve-1 Antibody | 103-M130 | ReliaTech
Species: Anti-Mouse
Host / biotech: Rat
Comment: N/A
Label: N/A
Clone / Antibody feature: (#4D17)
Subcategory: Monoclonal Antibody
Category: Antibody
Synonyms: Lyve1; Xlkd1; Lyve-1; Crsbp-1; 1200012G08Rik
Isotype: IgG2
Application: WB, IHC (F)
Detection Range: N/A
Species Reactivity/Cross reactivity: Mouse
Antigen: Mouse recombinant LYVE-1
Description: LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
Purity Confirmation: N/A
Endotoxin: N/A
Formulation: lyophilized
Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Molecular Weight: N/A
Lenght (aa): N/A
Protein Sequence: N/A
NCBI Gene ID: 114332
