Euro
USD
British Pound
NULL
Product Description
Rat Anti-Mouse Sonic Hedgehog (Shh) C-terminal Antibody | 103-M269 | ReliaTech
Species: Anti-Mouse
Host / biotech: Rat
Comment: N/A
Label: N/A
Clone / Antibody feature: (#4A37)
Subcategory: Monoclonal Antibody
Category: Antibody
Synonyms: Shh; Hx; Dsh; Hhg1; Hxl3; M100081; 9530036O11Rik
Isotype: IgG2
Application: WB
Detection Range: N/A
Species Reactivity/Cross reactivity: Mouse
Antigen: recombinant mouse Shh (C-terminal) fragment
Description: Human Shh cDNA encodes a 462 amino acid (aa) residue (45 kDa) precursor protein with a 23 aa signal peptide. An autocatalytic cleavage reaction yields a 19 kDa (residues 24 - 197) amino-terminal fragment (Shh-N), and a 25 kDa (residues 198 - 462) carboxy-terminal domain (Shh-C). The N-terminal domain retains all known signaling capabilities, while the C-terminal domain is responsible for the intramolecular processing, acting as a cholesterol transferase that covalently transfers the cholesterol molecule to the C-terminus of Shh-N. When Shh is expressed in insect or mammalian cells, a palmitoyl group is also attached to the N-terminal cysteine of Shh-N via an amide linkage.
Purity Confirmation: N/A
Endotoxin: N/A
Formulation: lyophilized
Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Molecular Weight: N/A
Lenght (aa): N/A
Protein Sequence: N/A
NCBI Gene ID: 20423
