Product Description
ASyO2 | Mouse anti-human alpha-synuclein | oligomer-specific (clone number 51, 24) | AS13 2717 | Agrisera
Immunogen: synthetic peptide derived from human alpha-synuclein Glu131-Ala140
Host: Mouse
Conjugation: N/A
Clonality: Monoclonal
Isotype: IgG1
Purity: Immunogen affinity purified serum in PBS pH 7.4.
Format: Lyophilized
Tested Application: Dot blot (Dot), ELISA (ELISA), Immunolocalization (IL)
Related Products: AS13 2718 | anti-ASyO5 | Mouse anti-human alpha-synuclein | oligomer-specific, monoclonal antibodiesAS13 2719 | anti-ASyM | Mouse anti-human alpha synuclein N-terminal, monoclonal antibodiesAS13 2717B | anti-ASyO2-biotinylated | Mouse anti-human alpha-synuclein | oligomer-specific, monoclonal antibodiesAS13 2718B | anti-ASyO5-biotinylated | Mouse anti-human alpha-synuclein | oligomer-specific, monoclonal antibodiesAS13 2719B | anti-ASyM-biotinylated | Mouse anti-human alpha synuclein N-terminal, monoclonal antibodiesAS08 358 | anti-SNCA | Alpha-synuclein, rabbit antibodies
Recommended Dilutions: 1-2 ug/ml (Dot), 2-4 ug/ml (ELISA capture), 10 ug/ml (IHC)
Molecular weight: 14 kDa
Confirmed Reactivity: Human
Predicted Reactivity: Mouse
Not reactive in: No confirmed exceptions from predicted reactivity are currently known
Additional Information: N/A
Background: Alpha-synuclein is normally an unstructured soluble protein that can aggregate to form insoluble fibrils in pathological conditions characterized by Lewy bodies, such as Parkinson's disease, dementia with Lewy-bodies, and multiple system atrophy. In analogy to many other amyloid associated disorders, alpha-synuclein may also form oligomeric assemblies. These small and soluble forms have been suggested to exert a stronger tissue damaging effect as compared to the monomeric and fibrillar counterpart. Using a recently developed technique a monoclonal oligomer-specific antibody has been designed.
Reconstitution: For reconstitution add 50 µl of sterile water
Storage: For short time storage please add sodium azide and srote at +4°C.For long time storage store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
TAIR Nnumbre: N/A
Category: Parkinson's disease
Research Area: Pathology, Amyloid Disorders